E2F4 Function in G2 Maintaining G2-arrest to Prevent Mitotic Entry with Damaged DNA
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چکیده
منابع مشابه
Arenobufagin intercalates with DNA leading to G2 cell cycle arrest via ATM/ATR pathway
Arenobufagin, a representative bufadienolide, is the major active component in the traditional Chinese medicine Chan'su. It possesses significant antineoplastic activity in vitro. Although bufadienolide has been found to disrupt the cell cycle, the underlying mechanisms of this disruption are not defined. Here, we reported that arenobufagin blocked the transition from G2 to M phase of cell cycl...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2007
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.6.10.4259